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POLYOMAVIRUS DETECTION (Ontario)

Test Details
Test Name : POLYOMAVIRUS DETECTION
Alternative Test Names : BK VIRUS DETECTION, JC VIRUS & BK VIRUS DETECTION, JC VIRUS DETECTION, POLYOMAVIRUS DETECTION
Code: PVD
Test Overview : JC and BK viruses are in the genus Polyomavirus and have similar genetic make -up. Patients in whom progressive multi-focal leukoencephalopathy (PML) is suspected (often HIV patients) should have a spinal fluid sent for testing. Although our test does not distinguish between JC and BK, positive results in spinal fluid samples are generally interpreted as positive for JC virus because PML is a disease of the central nervous system. Patients in whom nephritis is suspected (usually kidney transplant recipients) should have an EDTA (lavender) blood tube collected and the plasma is tested. Again, our test does not distinguish between JC and BK, but positive results in plasma from a kidney transplant patient are interpreted as positive for BK virus because BK virus infects the kidneys.
Test Preparation Instructions : For patients in whom progressive multi-focal leukoencephalopathy (PML) is suspected (often HIV patients) submit a spinal fluid for testing.
Turnaround Time: 15 DAYS
Reference Interval:
Age Reference Interval
Sex Low High Component Low High Units Note
M/F NEGATIVE 1
Age
Sex Low High Component
M/F

Reference Interval
Low High Units Note
NEGATIVE 1
(1)

This assay detects both JC and BK polyomaviruses but does
not differentiate between them. JC virus is found primarily
in the cerebral spinal fluid of individuals with
progressive multifocal leukoencephalopathy. BK virus is
assayed from plasma and is primarily associated with
allograft failure in renal transplant patients and renal
dysfunction in non-transplant patients.

Specimen Requirements
Specimen Type: Cerebral Spinal Fluid
Container: STERILE CONTAINER
Volume: 1.00mL

Collection Requirements: Collect 1 mL CSF in a sterile container. Specimen must be frozen within 24 hours of collection.
Storage and Transport: If specimen will be received at a Dynacare main lab location within 24 hours of collection, store and ship refrigerated. If not, store frozen and ship on dry ice.

OptimalRx Plus®

Formerly known as Genecept Assay®
New name. Same trusted results.