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ADAMTS13 ACTIVITY (Ontario)

Test Details
Test Name : ADAMTS13 ACTIVITY
Alternative Test Names : ADAMTS13 ACTIVITY, PROTEASE ACTIVITY FOR THROMBOTIC THROMBOCYTOPENIC PURPURA, PROTEASE ACTIVITY FOR TTP
Code: ADAM
Test Overview : May assist in diagnosing congenital or acquired thrombotic thrombocytopenic purpura (TTP).
Test Preparation Instructions : Collect specimens prior to transfusion of any components and prior to apheresis. Transfusion or apheresis with plasma prior to sample collection may mask deficiency.
Turnaround Time: 19 DAYS
Reference Interval:
Age Reference Interval
Sex Low High Component Low High Units Note
M/F > 0.40 Unit/Millilitre
Age
Sex Low High Component
M/F

Reference Interval
Low High Units Note
> 0.40 Unit/Millilitre
Specimen Requirements
Specimen Type: Platelet Poor Plasma
Container: LIGHT BLUE TOP (CITRATE)
Volume: 1.00mL

Collection Requirements: Specimen for this test must be collected, processed, aliquoted and frozen within 60 minutes of collection. If unable to meet these requirements, patients must be referred to a Dynacare Laboratory and Health Services Centre for collection. Collect 1 light blue top tube. Centrifuge and remove top 2/3 of plasma with a plastic transfer pipette into a transport tube being careful not to disturb the cell layer. Centrifuge plasma aliquot and transfer to 2nd transport tube, staying clear of the cell button at the bottom of the tube. Freeze immediately. Note: if the light blue top tube is the first vacutainer to be drawn, collect a small amount of blood in a discard tube before proceeding with the rest of the collection. A completed ADAMTS-13 Request Form must accompany the sample and can be downloaded from the site https://www.stmichaelshospital.com/programs/labs/tests
Storage and Transport: Store frozen. Ship on dry ice.

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