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PHOSPH. TAU-181 ELECSYS

Test Details
Test Name : PHOSPH. TAU-181 ELECSYS
Alternative Test Names : PHOSPHORYLATED TAU-181 ELECSYS
Code: P18E
Test Overview : This is a patient-pay test. The Elecsys® pTau-181 plasma assay result is intended to be used as an aid in the initial assessment for Alzheimer's disease and other causes of cognitive decline in adult patients ages 55 years and older presenting with signs, symptoms or complaints of cognitive decline. The result should be interpreted in conjunction with other clinical information. A negative test result is consistent with a negative amyloid positron emission tomography (PET) scan result and reduced likelihood that a patient's cognitive impairment is due to amyloid pathology. These patients should be investigated for other causes of cognitive decline. A positive test result may not be consistent with a positive amyloid PET scan result. Patients with an initial positive result should be further investigated to determine whether the amyloid pathology can be a cause of cognitive impairment. Methodology is Roche Diagnostics Electrochemiluminescence Immunoassay (ECLIA).
Test Preparation Instructions : N/A
Turnaround Time: 10 DAYS
Reference Interval:
Age Reference Interval
Sex Low High Component Low High Units Note
M/F 0.000 0.722 Picogram / Millilitre
Age
Sex Low High Component
M/F

Reference Interval
Low High Units Note
0.000 0.722 Picogram / Millilitre
(1)

Negative ( <=0.722 pg/mL)
A negative test result is consistent with a negative amyloid
PET scan result. These patients should be investigated for
causes of cognitive decline other than amyloid pathology.
Positive ( >0.722 pg/mL)
A positive result may not be consistent with a positive
amyloid PET scan result. Patients with an initial positive
result should be further investigated to determine whether
amyloid pathology can be a cause of cognitive impairment.
Test performed by Roche Diagnostics Electrochemiluminescence
Immunoassay (ECLIA)

Specimen Requirements
Specimen Type: Plasma
Container: LAVENDER TOP TUBE (EDTA)
Volume: 1.00mL

Collection Requirements: Centrifuge and aliquot plasma to a transport tube.
Storage and Transport: Store and ship refrigerated. If transport to Dynacare will be delayed, store and ship the sample frozen. Stability is 2 days at room temperature, 7 days refrigerated and 3 months frozen. Stable for X1 freeze/thaw cycle.

OptimalRx Plus®

Formerly known as Genecept Assay®
New name. Same trusted results.