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Test Details
Test Name : JOINTstat
Alternative Test Names : JOINTstat, 14-3-3, 14-3-3(eta)
Code: JNTS
Test Overview : JOINTstat is a blood test used to diagnose rheumatoid arthritis (RA). The test measures a protein in the blood, known as 14-3-3(eta) that is involved in biochemical pathways that lead to inflammation and joint degradation.
Test Preparation Instructions : N/A
Turnaround Time: 12 DAYS
Reference Interval:
Age Reference Interval
Sex Low High Component Low High Units Note
M/F < 0.19
Sex Low High Component

Reference Interval
Low High Units Note
< 0.19

Negative : < 0.19 ng/mL
Low positive : >= 0.19 - < 0.40 ng/mL
Moderate positive : >= 0.40 - < 0.80 ng/mL
High positive : >= 0.80 ng/mL
Carrier N, et al. Serum levels of 14-3-3n protein
supplement C-reactive protein and rheumatoid
arthritis-associated antibodies to predict clinical
and radiographic outcomes in a prospective
cohort of patients with recent-onset inflammatory
polyarthritis. Arthritis Res Ther 2016;18:37
Maksymowych WP, et al. 14-3-3n is a novel mediator
associated with the pathogenesis of rheumatoid
arthritis and joint damage. Arthritis Res Ther.

Specimen Requirements
Specimen Type: Serum
Container: SGT

Collection Requirements: Centrifuge.
Storage and Transport: Store frozen. Ship on dry ice.

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