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Test Details
Test Name : JOINTstat
Alternative Test Names : JOINTstat, 14-3-3, 14-3-3(eta)
Code: JNTS
Test Overview : JOINTstat is a blood test used to diagnose rheumatoid arthritis (RA). The test measures a protein in the blood, known as 14-3-3(eta) that is involved in biochemical pathways that lead to inflammation and joint degradation.
Test Preparation Instructions : N/A
Turnaround Time: 12 DAYS
Reference Interval:
Age Reference Interval
Sex Low High Component Low High Units Note
M/F < 0.19
Sex Low High Component

Reference Interval
Low High Units Note
< 0.19

Negative : < 0.19 ng/mL
Low positive : >= 0.19 - < 0.40 ng/mL
Moderate positive : >= 0.40 - < 0.80 ng/mL
High positive : >= 0.80 ng/mL
Carrier N, et al. Serum levels of 14-3-3n protein
supplement C-reactive protein and rheumatoid
arthritis-associated antibodies to predict clinical
and radiographic outcomes in a prospective
cohort of patients with recent-onset inflammatory
polyarthritis. Arthritis Res Ther 2016;18:37
Maksymowych WP, et al. 14-3-3n is a novel mediator
associated with the pathogenesis of rheumatoid
arthritis and joint damage. Arthritis Res Ther.

Specimen Requirements
Specimen Type: Serum
Container: SGT

Collection Requirements: Specimen may be collected in Dr's office and submitted as per routine samples but must arrive at Dynacare laboratory within 72 hours of collection. Samples will be frozen upon receipt in a Dynacare main lab facility. Centrifuge. Separate serum from cells. Aliquot serum to a transport tube.
Storage and Transport: If specimen will be received at a Dynacare main lab location within 72 hours of collection, store and ship refrigerated. If not, store frozen and ship on dry ice.

Genecept Assay®

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