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This testing will be performed using a laboratory developed test (LDT) which utilizes liquid chromatography with tandem mass spectrometry detection (LC-MS/MS) to replace the current method which uses liquid chromatography with electrochemical detection (LC-ECD). This new LC-MS/MS assay will provide enhanced specificity and is considered the gold standard analytical technique for this testing.
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Changes to 5-Hydroxyindoleacetic Acid 24-hour Urine and Vanillylmandelic Acid 24 hour Urine Testing effective June 28th, 2021